Glutathione, Premier

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Glutathione, Premier, Reduced GSH Antioxidant, Detoxification, and Liver Support (30 vcaps)

Premier Glutathione is a free radical quencher that promotes Phase I and Phase II liver detoxification along with nerve and immune system support.

It contains reduced L-glutathione along with reishi, organic bladderwrack, turmeric, red algae, yerba santa, and others to have an even more powerful effect.

In a Journal entitled Biochemistry (Moscow) 2014, the authors explain some of the important roles that glutathione plays....

"Reduced glutathione (GSH) is a tripeptide consisting of the amino acids L-glutamate, L-cysteine, and glycine. ... this peptide is also an intracellular antioxidant that scavenges free radicals, plays the role of the cosubstrate in the reaction of peroxide detoxification catalyzed by glutathione peroxidase (GPx) and glutathione transferase (GST), and reduces oxidized glutaredoxin (Grx), which is necessary for the reduction of disulfides [3-5]. Maintenance of the GSH/GSSG ratio at the optimal level is important for cell vitality. A decrease in the GSH content below the normal level may indicate the disturbance of cellular redox status and change in the redox dependent regulation of genes. Alteration of intracellular GSH balance is observed in a number of pathologies including malignant tumors.... neurodegenerative diseases, mucoviscidosis, and HIV infection [6]....

GSH/GSSG balance affects antioxidant defense, energy production, DNA repair, apoptosis, signaling, transcription, protein folding, differentiation."

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